The black market for weight-loss drugs in South Africa is a growing concern, with unauthorized products like retatrutide being sold and injected despite clinical trials and regulatory approval. The popularity of these drugs highlights the public's desire for quick solutions to obesity, but the lack of approval raises safety questions. Dr. Tracy Nelwamondo, a GP with a special interest in doctor-led weight management, warns that the lack of knowledge about the drug's interactions with the human body and other medicines is a significant risk. The drug's remarkable weight-loss results, even greater than those of similar drugs like Ozempic and Mounjaro, have fueled its popularity, but the potential for unknown side effects and health risks is a major concern. The drug is not yet approved for commercial sale or human use, and the Mail and Guardian article reports that it is being promoted widely on social media and in health and wellness spaces, including gyms. The article also highlights the methods by which these illegal products are reaching consumers, including personal contacts, online sellers, and informal suppliers. The black market for weight-loss drugs in South Africa is a complex issue that requires careful consideration and regulation to ensure the safety and well-being of the public.